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An extranuclear locus of cAMP-dependent protein kinase action is necessary and sufficient for promotion of spiral ganglion neuronal survival by cAMP.

Bok J, Zha XM, Cho YS, Green SH
J Neurosci. 2003 Feb 1;23(3):777-87. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
61091GPKAGFP-tagged cAMP-dependent PKA catalytic subunit
61092GPKAnesGFP-tagged PKA catalytic subunit targeted to the extranuclear cytoplasm by addition of a nuclear export signal
61094GPKAnlsGFP-tagged PKA catalytic subunit targeted to the nucleus by addition of a nuclear localization signal

Antibodies from Article