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Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia.

Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marban E, Jan LY, Shaw RM
Nat Med. 2014 Jun;20(6):624-32. doi: 10.1038/nm.3543. Epub 2014 May 18. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
61086pDest27-mBIN1Express N-terminal GST tagged-mouse BIN1 in mammalian cells
61087pDest27-mBIN1+13Express N-terminal GST tagged-mouse BIN1+13 in mammalian cells
61096pDest27-mBIN1+17Express N-terminal GST tagged-mouse BIN1+17 in mammalian cells
61097pDest27-mBIN1+13+17Express N-terminal GST tagged-mouse BIN1+13+17 in mammalian cells

Antibodies from Article