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PTPN14 forms a complex with Kibra and LATS1 proteins and negatively regulates the YAP oncogenic function.

Wilson KE, Li YW, Yang N, Shen H, Orillion AR, Zhang J
J Biol Chem. 2014 Aug 22;289(34):23693-700. doi: 10.1074/jbc.M113.534701. Epub 2014 Jul 14. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
61003pCDNA3-V5-PTPN14-wild typeExpresses wild type human PTPN14 in mammalian cells, N-terminus V5 tag
61004pCDNA3-V5-PTPN14-del-NExpresses human PTPN14 (del-FERM domain mutant) in mammalian cells, N-terminus V5 tag
61005pCDNA3-V5-PTPN14-del-CExpresses human PTPN14 (del-phosphotase domain mutant) in mammalian cells, N-terminus V5 tag
61006pCDNA3-V5-PTPN14-PPxYExpresses human PTPN14 (PPxY domain mutant) in mammalian cells, N-terminus V5 tag

Antibodies from Article