The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse.
Savolainen MH, Richie CT, Harvey BK, Mannisto PT, Maguire-Zeiss KA, Myohanen TT
Neurobiol Dis. 2014 Aug;68:1-15. doi: 10.1016/j.nbd.2014.04.003. Epub 2014 Apr 16.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 59967 | pOTTC414 - pAAV EF1a hPREP | An AAV packaging vector that expresses hPREP under control of the EF1a promoter. |
| 59968 | pOTTC446 - pAAV EF1a hPREP(S554A) | An AAV packaging vector that expresses catalytically-inactive hPREP under control of the EF1a promoter. |
| 60057 | pOTTC293 - pAAV EF1a V5-synuclein (WT) | An AAV packaging vector that expresses wildtype alpha-synuclein under control of the EF1a promoter. |
| 60058 | pOTTC407 - pAAV EF1a eGFP | An AAV packaging vector that expresses enhanced green fluorescent protein under control of the EF1a promoter. |