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A role for WDR5 in integrating threonine 11 phosphorylation to lysine 4 methylation on histone H3 during androgen signaling and in prostate cancer.

Kim JY, Banerjee T, Vinckevicius A, Luo Q, Parker JB, Baker MR, Radhakrishnan I, Wei JJ, Barish GD, Chakravarti D
Mol Cell. 2014 May 22;54(4):613-25. doi: 10.1016/j.molcel.2014.03.043. Epub 2014 May 1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
59969pGEX-4T1-WDR5Bacterial Expression GST-WDR5
59970pCMX-PL1-WDR5Mammalian Expression of WDR5
59974p3XFLAG-CMV-14-WDR5Mammalian Expression of WDR5-FLAG
59975pSuper.Retro.Puro-WDR5 shRNA 2Knockdown of WDR5
59977pSuper.Retro.Puro-WDR5 shRNA 4Knockdown of WDR5
59978pSuper.Retro.Puro-PKN1 shRNA 4Knockdown of PKN1

Antibodies from Article