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Protein phosphatase 2A and separase form a complex regulated by separase autocleavage.

Holland AJ, Bottger F, Stemmann O, Taylor SS
J Biol Chem. 2007 Aug 24;282(34):24623-32. Epub 2007 Jun 29. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
59824pcDNA5 FRT TO myc Separase delta 55Allows the integration of myc Separase delta 55 in the genome and Tet-inducible expression.
59825pcDNA5 FRT TO myc Separase delta 55/S1126AAllows the integration of myc Separase delta 55/S1126A in the genome and Tet-inducible expression.
59826pcDNA5 FRT TO myc Separase Non-CleavableAllows the integration of myc Separase Non-Cleavable in the genome and Tet-inducible expression.
59827pcDNA5 FRT TO myc Separase delta 55/Non-CleavableAllows the integration of myc Separase delta 55/Non-Cleavable in the genome and Tet-inducible expression.
59830pcDNA5 FRT TO myc Separase delta 1278-1291Allows the integration of myc Separase delta 1278-1291 in the genome and Tet-inducible expression.

Antibodies from Article