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The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration.

Broussard JA, Lin WH, Majumdar D, Anderson B, Eason B, Brown CM, Webb DJ
Mol Biol Cell. 2012 Apr;23(8):1486-99. doi: 10.1091/mbc.E11-02-0124. Epub 2012 Feb 29. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
59767GFP-APPL1-R146A/K152A/R154AExpresses APPL1 Endosomal Localization Mutant
59768GFP-APPL1-ΔPTBExpresses APPL1 with PTB domain deleted

Antibodies from Article