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Optical control of muscle function by transplantation of stem cell-derived motor neurons in mice.

Bryson JB, Machado CB, Crossley M, Stevenson D, Bros-Facer V, Burrone J, Greensmith L, Lieberam I
Science. 2014 Apr 4;344(6179):94-7. doi: 10.1126/science.1248523. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
59593tol2-GFAP::CD14Magnetic cell sorting of ES cell-derived astrocytes
59740tol2-CAG::ChR2-YFPOptogenetic excitation of ES cell-derived neurons (and other cells, such as muscle)
78209CAG::Gdnfpiggybac vector for mouse Gdnf expression

Antibodies from Article