KRAS and YAP1 Converge to Regulate EMT and Tumor Survival.
Shao DD, Xue W, Krall EB, Bhutkar A, Piccioni F, Wang X, Schinzel AC, Sood S, Rosenbluh J, Kim JW, Zwang Y, Roberts TM, Root DE, Jacks T, Hahn WC
Cell. 2014 Jul 3;158(1):171-84. doi: 10.1016/j.cell.2014.06.004. Epub 2014 Jun 19.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 59140 | pLX304-FOS-V5 | wild-type FOS with C-terminal V5 tag expressed from pLX vector |
| 59141 | pLX304-YAP1 _SH3bm | YAP1 mutants that harbored a deletion of SH3 binding motif, which disrupts interaction of YES1 with YAP1 |
| 59143 | pLX304-YAP1 _TA | YAP1 mutants that harbor a deletion of the transcriptional activation domain |
| 59144 | pLX304-YAP1 _60-89 | YAP1 mutants that harbored a deletion of amino acide at 60-89 position, which disrupts binding to TEAD transcription factors |
| 59145 | pLX304-YAP1(S94A) | YAP1 serine 94 o alanine mutants which disrupts binding to TEAD transcription factors |
| 59147 | pLX304-YAP1 _PDZ | YAP1 mutants that harbored a deletion of the 5 amino acids |
| 59913 | TGMP.shKras.1422 | Tet on shKras for conditional Kras knockdown |
| 59915 | TRMPVneo.Yap.3093 | Tet on shRNA for conditional Yap1 knockdown |
| 116871 | Tet-pLKO-puro shKRAS | Tet-inducible suppression of KRAS |