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The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation.

Meyers S, Lenny N, Hiebert SW
Mol Cell Biol. 1995 Apr . 15(4):1974-82. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
12426pCMV5-AML1BpCMV5-AML1B is the original plasmid used in Meyers et al 1995. However, please note that the insert sequence has now been identified as AML1C.
12427pCMV5-CBFbeta
12428pCMV-AML1-ETO

Antibodies from Article