Cyclin D activates the Rb tumor suppressor by mono-phosphorylation.

Narasimha AM, Kaulich M, Shapiro GS, Choi YJ, Sicinski P, Dowdy SF
Elife. 2014 May 29:e02872. doi: 10.7554/eLife.02872. PubMed Article

Plasmids from Article

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ID	Plasmid	Purpose
58921	pCMV HA hRB delta CDK + T826	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and T826 restored
58920	pCMV HA hRB delta CDK + T821	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and T821 restored
58919	pCMV HA hRB delta CDK + S811	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and S811 restored
58918	pCMV HA hRB delta CDK + S807	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and S807 restored
58916	pCMV HA hRB delta CDK + S788	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and S788 restored
58915	pCMV HA hRB delta CDK + S780	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and S780 restored
58914	pCMV HA hRB delta CDK + S612	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and S612 restored
58913	pCMV HA hRB delta CDK + S608	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and S608 restored
58912	pCMV HA hRB delta CDK + T373	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and T373 restored
58911	pCMV HA hRB delta CDK + T356	mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and T356 restored