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Spatial dynamics of chromosome translocations in living cells.

Roukos V, Voss TC, Schmidt CK, Lee S, Wangsa D, Misteli T
Science. 2013 Aug 9;341(6146):660-4. doi: 10.1126/science.1237150. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
58505pLacO-ISce1provides 256 Lac operator repeats adjacent to the ISce1 restriction site
58506pTetO-ISce1-TetOISce1 restriction site is flanked by Tet operator repeats, 96 on each side
59417pQCXIN-TetR-mCherryretroviral construct expressing the Tet repressor (TetR) tagged with mCherry
59418pQCXIP-GFP-LacRretroviral construct expressing the Lac repressor (LacR) tagged with GFP
59424HA-ISceID44AExpresses a catalytically inactive form of the endonuclease ISceI

Antibodies from Article