Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification.
Guilinger JP, Thompson DB, Liu DR
Nat Biotechnol. 2014 Apr 25. doi: 10.1038/nbt.2909.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
52970 | FokI-dCas9 | Expresses Fok1 nuclease domain fused to catalytically inactive Cas9 DNA-binding domain in mammalian cells |