CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis.
Huot G, Vernier M, Bourdeau V, Doucet L, Saint-Germain E, Gaumont-Leclerc MF, Moro A, Ferbeyre G
Mol Biol Cell. 2014 Mar;25(5):554-65. doi: 10.1091/mbc.E13-02-0110. Epub 2014 Jan 8.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 51836 | pLPC-Flag-CHES1L | encodes the long isoform of human CHES1 and a Flag tag |
| 51837 | pLPC-Flag-CHES11L-dFC | Flag-CHES1L mutant lacking the forkhead binding site and the C-terminal domains |
| 51838 | pLPC-Flag-CHES1LdFC-NLS | Flag-CHES1L mutant lacking the forkhead binding site and C-terminal domain, with remaining NLS |
| 51839 | pLPC-Flag-CHES1L-dC | Flag-CHES1L mutant lacking the C-terminal and NLS domains |
| 51840 | pLPC-Flag-CHES1L-dC-NLS | Flag-CHES1L mutant lacking the C-terminal, with remaining NLS |
| 51841 | pLPC-Flag-CHES1L-DBD-NLS | Flag-CHES1L mutant encoding the DNA binding and NLS domains only |
| 51842 | pLPC-Flag-CHES1L-dFN | Flag-CHES1L mutant lacking the forkhead binding site and N-terminal domains |
| 51843 | pLPC-Flag-CHES1L-dN | Flag-CHES1L mutant lacking the N-terminal domain |
| 51844 | pLPC-Flag-CHES1H164A | Flag-CHES1L mutant with ponctual mutation on histidine 164 |
| 51845 | mlp-hCHES1sh | shRNA against CHES1 |
| 51846 | pBabe-CHES1-ER | fusion protein between CHES1 and the ligand binding domain of estrogen receptor |
| 51847 | pWZL-rCHES1 | encodes a CHES1 mRNA that is resistant to shRNA against CHES1 |
| 51848 | pGL3-PIM2 | promoter region (-550;0) of PIM2 |
| 51849 | pGL3-PIM2mut1 | promoter region of PIM2 lacking the forkhead binding site #2 |
| 51850 | pGL3-PIM2mut2 | promoter region of PIM2 lacking the forkhead binding site #1 |
| 53742 | pGL3-PIM2mut3 | promoter region of PIM2 lacking the 2 forkhead binding sites |
| 53743 | pLPC-CHES1L | long isoform of human CHES1 |