miR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3zeta.
Jung HM, Phillips BL, Chan EK
Mol Cancer. 2014 Apr 8;13(1):80. doi: 10.1186/1476-4598-13-80.
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PubMed
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 53694 | pMiR-E6AP-3'UTR | Luciferase reporter assay for microRNA binding on E6AP 3'UTR |
| 53695 | pMiR-E6AP-3'UTR-miR-375-mut | Luciferase reporter assay for E6AP 3'UTR with point mutation on miR-375 binding site |
| 53696 | pMiR-HPV16-E7 | Luciferase reporter assay for microRNA binding on HPV16 E7 |
| 53697 | pMiR-HPV16-E7-m1 | Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site |
| 53698 | pMiR-HPV16-E7-m2 | Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site |
| 53699 | pMiR-HPV16-E1(partial) | Luciferase reporter assay for microRNA binding on HPV16 E1 |
| 53700 | pMiR-HPV16-E1-m3 | Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site |
| 53701 | pMiR-HPV16-E1-m4 | Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site |
| 53702 | pMiR-HPV16-E1-m5 | Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site |
| 53703 | pMiR-HPV16-E7/E1 | Luciferase reporter assay for microRNA binding on HPV16 E7/E1 |
| 53704 | pMiR-HPV16-E7/E1-miR-375-m1-5 | Luciferase reporter assay for HPV16 E7/E1 with point mutation on miR-375 binding site |