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The 5' guanosine tracts of human telomerase RNA are recognized by the G-quadruplex binding domain of the RNA helicase DHX36 and function to increase RNA accumulation.

Sexton AN, Collins K
Mol Cell Biol. 2011 Feb;31(4):736-43. doi: 10.1128/MCB.01033-10. Epub 2010 Dec 13. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
53546pBABE Hygro Flag hTERTretroviral expression of human TERT
53547pcDNA3.1 TAP DHX36mammalian expression of DHX36

Antibodies from Article