The 5' guanosine tracts of human telomerase RNA are recognized by the G-quadruplex binding domain of the RNA helicase DHX36 and function to increase RNA accumulation.
Sexton AN, Collins K
Mol Cell Biol. 2011 Feb;31(4):736-43. doi: 10.1128/MCB.01033-10. Epub 2010 Dec 13.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
53546 | pBABE Hygro Flag hTERT | retroviral expression of human TERT |
53547 | pcDNA3.1 TAP DHX36 | mammalian expression of DHX36 |