Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains.
Volmer R, van der Ploeg K, Ron D
Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4628-33. doi: 10.1073/pnas.1217611110. Epub 2013 Mar 4.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 54337 | Flag_HsIRE1a_pBabePuro | N-terminally FLAG tagged human IRE1a in retroviral pBabe puro vector |
| 58422 | Flag_HsIRE1a_deltaP29_D408_pBabePuro | retroviral pBabe puro vector encoding N-terminally FLAG tagged mutant human IRE1a deleted from amino acids P28 to D408 |
| 58423 | Flag_MmPERK_S503_N1114_pBabePuro | retroviral pBabe puro vector encoding N-terminally FLAG tagged mutant mouse PERK deleted from amino acids M1 to Y502. The remaining amino acids are S503 to N1114. |
| 58492 | Flag_HsIRE1a_deltaP29_D408_K599A_pBabePuro | retroviral pBabe puro vector encoding N-terminally FLAG tagged mutant human IRE1a deleted from amino acids P28 to D408 and bearing mutation K599A (kinase domain mutant) |