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p21-activated kinase links Rac/Cdc42 signaling to merlin.

Xiao GH, Beeser A, Chernoff J, Testa JR
J Biol Chem. 2002 Jan 11. 277(2):883-6. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
12212pCMV6M-Pak1 L107F
12214pEBG-Pak1 83-149
12215pEBG-Pak1 83-149 L107F
12216pGEX-Pak1 83-149
84293pEGFP-MerlinExpression of wt Merlin
84294pEGFP-Merlin S518AExpression of Merlin with an alanine mutation at the Pak phosphorylation site
84295pEGFP-Merlin S518DExpression of Merlin with a phosphomimic (aspartic acid) mutation at the Pak phosphorylation site

Antibodies from Article