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A structural basis for drug-induced long QT syndrome.

Mitcheson JS, Chen J, Lin M, Culberson C, Sanguinetti MC
Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12329-33. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
53051pSP64-hERG1aExpresses alpha subunit of hERG1a K channel in Xenopus oocytes
53052pCEP4-hERG1aExpresses alpha subunit of hERG1a K channel in mammalian cells
53053pSP64-hERG1a Y652AExpresses alpha subunit of Y652A hERG1a K channel in Xenopus oocytes
53054pSP64-hERG1a F656AExpresses alpha subunit of F656A hERG1a K channel in Xenopus oocytes
53055pSP64-hERG1a T623AExpresses alpha subunit of T623A hERG1a K channel in Xenopus oocytes
53056pSP64-hERG1a S624AExpresses alpha subunit of S624A hERG1a K channel in Xenopus oocytes

Antibodies from Article