Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2.
Bamming D, Horvath CM
J Biol Chem. 2009 Apr 10;284(15):9700-12. doi: 10.1074/jbc.M807365200. Epub 2009 Feb 11.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
52875 | pEF-Bos-FLAG MDA5 MI | Expresses MDA5 with a mutation to motif I in mammalian cells |
52876 | pEF-Bos-FLAG MDA5 MIII | Expresses MDA5 with a mutation to motif III in mammalian cells |
52877 | pEF-Bos-FLAG RIG-I MIII | Expresses RIG-I with a mutation to motif III in mammalian cells |
58681 | CMV-10-3xFLAG-LGP2 | Expresses 3x Flag-tagged LGP2 in mammalian cells |
58682 | CMV-10-3xFLAG-LGP2-MI | Expresses LGP2 with a mutation to motif I in mammalian cells |
58683 | CMV-10-3xFLAG-LGP2-MIII | Expresses LGP2 with a mutation to motif III in mammalian cells |