A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Escribano-Diaz C, Orthwein A, Fradet-Turcotte A, Xing M, Young JT, Tkac J, Cook MA, Rosebrock AP, Munro M, Canny MD, Xu D, Durocher D
Mol Cell. 2013 Mar 7;49(5):872-83. doi: 10.1016/j.molcel.2013.01.001. Epub 2013 Jan 17.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 52504 | pDEST 3x Flag-pcDNA5-FRT/T0-BRCA1 | mammalian expression vector of BRCA1 wildtype siRNA resistant |
| 52505 | pDEST 3xFlag-pcDNA5-FRT/T0-53BP1 28A | mammalian expression vector of 53BP1 28A mutant |
| 52506 | pDEST pcDNA5-FRT/TO-eGFP-Rif1 | mammalian expression vector of Rif1 siRNA resistant |
| 52507 | pcDNA5-FRT/T0-Flag-53BP1 | mammalian expression vector of 53BP1 |