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Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning.

Cai SL, Tee AR, Short JD, Bergeron JM, Kim J, Shen J, Guo R, Johnson CL, Kiguchi K, Walker CL
J Cell Biol. 2006 Apr 24. 173(2):279-89. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
12131Flag TSC2 2A(S939A + S981A)
12132Flag TSC2 wt
12133pcDNA3.1 myc TSC1

Antibodies from Article