Dicer recognizes the 5' end of RNA for efficient and accurate processing.
Park JE, Heo I, Tian Y, Simanshu DK, Chang H, Jee D, Patel DJ, Kim VN
Nature. 2011 Jul 13;475(7355):201-5. doi: 10.1038/nature10198.
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PubMed
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 51368 | pcDNA3.1-FLAG-Dicer-5'-pocket mutant | |
| 51369 | pcDNA3.1-FLAG-Dicer-Y926F/R927A (3'-pocket mutant) |