Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.
Ko M, An J, Bandukwala HS, Chavez L, Aijo T, Pastor WA, Segal MF, Li H, Koh KP, Lahdesmaki H, Hogan PG, Aravind L, Rao A
Nature. 2013 May 2;497(7447):122-6. doi: 10.1038/nature12052. Epub 2013 Apr 7.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 49446 | FH-TET3-pEF | This plasmid expresses full-length human TET3. |
| 68553 | Myc-Idax WT | This plasmid expresses full length IDAX. |
| 68554 | Myc-Idax DBM | This plasmid expresses full length IDAX containing a DNA binding mutation. |
| 127895 | FH-TET3-CXXCmut-pEF | Expresses ten-eleven-translocation 3 (TET3) containing CXXC mutation 80THQ82 to AAA |
| 127896 | FH-TET3-HxDmut-pEF | Expresses ten-eleven-translocation 3 (TET3) containing HxD mutation at H1077Y and D1079A |