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Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines.

Kane LP, Andres PG, Howland KC, Abbas AK, Weiss A
Nat Immunol. 2001 Jan;2(1):37-44. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
49267MSCV-myrAktretroviral expression of Bovine Akt with the NH2-terminal myristylation-palmitylation signal sequence

Antibodies from Article