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GSK3beta phosphorylation of the KLF6 tumor suppressor promotes its transactivation of p21.

Lang UE, Kocabayoglu P, Cheng GZ, Ghiassi-Nejad Z, Munoz U, Vetter D, Eckstein DA, Hannivoort RA, Walsh MJ, Friedman SL
Oncogene. 2012 Oct 22. doi: 10.1038/onc.2012.457. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
49488flag-hKLF6 (1006)expresses human flag tagged KLF6 in mammalian cells
49489flag-hKLF6-4A (1010)expresses human Flag tagged KLF6 with 4A mutation
49490Flag-KLF6-4D (1054)expresses human Flag tagged KLF6 with 4D mutation
49491GSK3beta  (1015)expresses human Gsk3beta
49492GSK3betaS9A  (1016)expresses human Gsk3beta with S9A (constitutively active) mutation
49496flag-hKLF6 P149S  (1008)expresses human Flag tagged KLF6 with P149S mutation
49497hKLF6 P148L (1009)expresses human KLF6 with P148L mutation

Antibodies from Article