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An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

Boyd SD, Tsai KY, Jacks T
Nat Cell Biol. 2000 Sep . 2(9):563-8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
12086pCMV HDM2(C464A)
12087pCMV HDM2(NES-)
12091GFP-p53
12092GFP-p53 (NES-)

Antibodies from Article