Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.
Calvo SE, Pagliarini DJ, Mootha VK
Proc Natl Acad Sci U S A. 2009 May 5;106(18):7507-12. doi: 10.1073/pnas.0810916106. Epub 2009 Apr 16.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 48158 | psicheck-2-Acsm2 | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48159 | psicheck-2-Acsm2 mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> TTG) upstream open reading from element |
| 48160 | psicheck-2-Slc25a15 | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48161 | psicheck-2-Slc25a15 mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> TTG) upstream open reading from element |
| 48162 | psicheck-2-Phb | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48163 | psicheck-2-Phb mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> TTG) upstream open reading from element |
| 48164 | psicheck-2-Mut | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48165 | psicheck-2-Mut mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> TTG) upstream open reading from element |
| 48166 | psicheck-2-Mrpl1 | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48167 | psicheck-2-LPPRC | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48168 | psicheck-2-LPPRC-mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> TTG) upstream open reading frame element |
| 48169 | psicheck-2-Sfxn3 | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48170 | psicheck-2-Sfxn3-mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> TTG) upstream open reading frame element |
| 48171 | psicheck-2-Casp8-mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> ATT) upstream open reading frame element |
| 48172 | psicheck-2-Casp8 | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48173 | psicheck-2-Mc2r-mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> GTG) upstream open reading frame element |
| 48174 | psicheck-2-Mc2r | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48175 | psicheck-2-Tas2r3-mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> ACG) upstream open reading frame element |
| 48176 | psicheck-2-Tas2r3 | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48177 | psicheck-2-Kdr-mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> GTG) upstream open reading frame element |
| 48178 | psicheck-2-Kdr | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48179 | psicheck-2-Hsdl2 | contains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame element |
| 48180 | psicheck-2-Hsdl2-mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> TTG) upstream open reading frame element |
| 49569 | psicheck-2-Mrpl11-mod | contains Renilla Luciferase gene preceded by a mutated (ATG --> TTG) upstream open reading frame element |