A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM
Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 46326 | C terminal Flag Mios pRK5 | |
| 46327 | HA Depdc5 pRK5 | |
| 46328 | Cterminal HA WDR59 pRK5 | |
| 46329 | Cterminal HA Mios pRK5 | |
| 46330 | HA Nprl3 pRK5 | |
| 46331 | HA Seh1L pRK5 | |
| 46332 | HA Sec13 pRK5 | |
| 46333 | Flag Nprl2 pRK5 | |
| 46334 | Flag WDR24 pRK5 | |
| 46335 | HA WDR24 pRK5 | |
| 46336 | Flag Depdc5 pLJM1 | |
| 46337 | Flag WDR24 pLJM1 | |
| 46338 | Flag Nprl2 pLJM1 | |
| 46340 | Flag Depdc5 pRK5 | |
| 46341 | Flag Leucyl tRNA synthetase pRK5 | |
| 46380 | eGFP Depdc5 pLJM1 |