TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends.
Zhong FL, Batista LF, Freund A, Pech MF, Venteicher AS, Artandi SE
Cell. 2012 Aug 3;150(3):481-94. doi: 10.1016/j.cell.2012.07.012.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
51631 | pCDH-3xFLAG-TERT | Mammalian expression of 3xFLAG tagged TERT, N-terminal. |
53585 | pCDNA-3xFLAG-NLS-TPP1 | Mammalian expression of 3xFLAG tagged, nuclear localized TPP1, N-terminal. |
79060 | pBABE-3xFLAG-NLS-TPP1-OB | Retroviral expression of 3xFLAG tagged, nuclear localized wild-type TPP1-OB folding domain |
79061 | pBABE-3xFLAG-OB D166R | Retroviral expression of 3xFLAG tagged, nuclear localized TPP1-OB-RR folding domain |