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Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

Ben-Sahra I, Howell JJ, Asara JM, Manning BD
Science. 2013 Mar 15;339(6125):1323-8. doi: 10.1126/science.1228792. Epub 2013 Feb 21. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
46238pcDNA3-FLAG-HA-CADFor expression of HA and FLAG-tagged murine CAD in mammalian cells
46239pcDNA3-FLAG-HA-CAD S1859AFLAG-HA-CAD with S1859 phosphorylation site mutated to alanine
46240pcDNA3-FLAG-HA-CAD S1900AFLAG-HA-CAD with S1900 mutated to alanine

Antibodies from Article