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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.

Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A
Nature. 2010 Dec 9;468(7325):839-43. doi: 10.1038/nature09586. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
41710FH-Tet2-pEFThis plasmid expresses mouse Tet2 with N-terminal FLAG and HA tags in a mammalian system

Antibodies from Article