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Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms.

Ueki K, Kondo T, Kahn CR
Mol Cell Biol. 2004 Jun . 24(12):5434-46. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
11486pCMV SOCS-3

Antibodies from Article