Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.
Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L, Scott MP, Beachy PA
Nature. 2000 Aug 31;406(6799):1005-9.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 37673 | pGEN-mSmo | |
| 37674 | pGEN-mSmoA1 |