Mislocalization of the E3 ligase, beta-transducin repeat-containing protein 1 (beta-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt.
Warfel NA, Niederst M, Stevens MW, Brennan PM, Frame MC, Newton AC
J Biol Chem. 2011 Jun 3;286(22):19777-88. Epub 2011 Mar 28.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 37100 | pcDNA3 HA-PHLPP1 full length | Expresses HA tagged, full-length human PHLPP1 in mammalian cells |