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Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.

Koivunen P, Lee S, Duncan CG, Lopez G, Lu G, Ramkissoon S, Losman JA, Joensuu P, Bergmann U, Gross S, Travins J, Weiss S, Looper R, Ligon KL, Verhaak RG, Yan H, Kaelin WG Jr
Nature. 2012 Feb 15;483(7390):484-8. doi: 10.1038/nature10898. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
36948FLAG-Venus-pLenti6
36950FLAG-EglN2-pLenti6
36951FLAG-EglN3-pLenti6

Antibodies from Article