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A KLF4-miRNA-206 autoregulatory feedback loop can promote or inhibit protein translation depending upon cell context.

Lin CC, Liu LZ, Addison JB, Wonderlin WF, Ivanov AV, Ruppert JM
Mol Cell Biol. 2011 Jun;31(12):2513-27. Epub 2011 Apr 25. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
34589pBpuro - HA KLF4 FL
34592pBpuro - HA KLF4 FL delta K5S
34593pcDNA3.1 - HA-KLF4 FL
34594pcDNA3.1 - HA-KLF4 FL delta K5S
34595pLJD vector
34596pLJD-KLF4-ER
34597pMIR-Report-Luc-KLF4-FL
34598pMIR-Report-Luc-KLF4-K5S
34599pMIR-Report-Luc-KLF4-K5S-Mt206A
34600pMIR-Report-Luc-KLF4-K5S-Mt206B
34601pMIR-Report-Luc-KLF4-K5S-Mt344A
34602pMIR-Report-Luc-KLF4-K5S-Mt344B
62979pMIR-Report-Luc-KLF4-K1STranslational reporter for KLF4
62980pMIR-Report-Luc-KLF4-K2STranslational reporter for KLF4
62981pMIR-Report-Luc-KLF4-K3STranslational reporter for KLF4
62982pMIR-Report-Luc-KLF4-K4STranslational reporter for KLF4
62983pMIR-Report-Luc-KLF4-K6STranslational reporter for KLF4

Antibodies from Article