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High-throughput screening for TLR3-IFN regulatory factor 3 signaling pathway modulators identifies several antipsychotic drugs as TLR inhibitors.

Zhu J, Smith K, Hsieh PN, Mburu YK, Chattopadhyay S, Sen GC, Sarkar SN
J Immunol. 2010 May 15;184(10):5768-76. Epub 2010 Apr 9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
32712hTLR3-pcDNA3
32713Human V5-IRF3-pcDNA3

Antibodies from Article