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Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling.

Koivusalo M, Welch C, Hayashi H, Scott CC, Kim M, Alexander T, Touret N, Hahn KM, Grinstein S
J Cell Biol. 2010 Feb 22;188(4):547-63. Epub 2010 Feb 15. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
32001mCherry-SEpHluorin
32002Lyn-tailed mCherry-SEpHluorin

Antibodies from Article