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The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia-like disease by bcr/abl.

He Y, Wertheim JA, Xu L, Miller JP, Karnell FG, Choi JK, Ren R, Pear WS.
Blood. 2002 Apr 15;99(8):2957-68. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
274791-63 bcr/abl pcDNA3
27481P210 pcDNA3
27483Mig P190 (Mig 185)
27486NGFR P210
27487NGFR 210Y177

Antibodies from Article