TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity.
Johnson BS, Snead D, Lee JJ, McCaffery JM, Shorter J, Gitler AD
J Biol Chem. 2009 Jul 24. 284(30):20329-39.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 27447 | pRS416Gal TDP43 WT YFP | |
| 27448 | pRS416 Gal G294A YFP | |
| 27449 | pRS416 Gal M337V YFP | |
| 27450 | pRS416 Gal Q331K YFP | |
| 27451 | pCold TDP43 WT | |
| 27452 | pCold TDP43 G294A | |
| 27453 | pCold TDP43 M337V | |
| 27454 | pCold TDP43 Q331K | |
| 27458 | pRS416 Gal TDP43 WT | |
| 27459 | pRS416 Gal TDP43 G294A | |
| 27460 | pRS416 Gal TDP43 M337V | |
| 27461 | pRS416 Gal TDP43 Q331K | |
| 27462 | pDuet TDP43 WT | |
| 27463 | pDuet TDP-43 G294A | |
| 27464 | pDuet TDP-43 M337V | |
| 27465 | pDuet TDP-43 Q331K |