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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T
Nat Immunol. 2003 May;4(5):491-6. (Link opens in a new window) PubMed (Link opens in a new window) Article

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