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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.

Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA
Nature. 2009 Mar 26. 458(7237):514-8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
41552pCI-Caspase 1
41553pCI-ASC-HA

Antibodies from Article