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SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation.

Jing E, Gesta S, Kahn CR
Cell Metab. 2007 Aug . 6(2):105-14. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
66144pBabe-SIRT2Expresses SIRT2 via retroviral method
66164FoxO1 KAExpresses FoxO1 with three Lys residues surrounding Ser-253 that are known to be sites of acetylation were replaced by alanine residues.
66165FoxO1 KQExpresses FoxO1 with three Lys residues surrounding Ser-253 that are known to be sites of acetylation were replaced by glutamine residues.
66166FoxO1 KRExpresses FoxO1 with three Lys residues surrounding Ser-253 that are known to be sites of acetylation were replaced by arginine residues.

Antibodies from Article