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The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer.

Nolan ME, Aranda V, Lee S, Lakshmi B, Basu S, Allred DC, Muthuswamy SK.
Cancer Res. 2008 Oct 15;68(20):8201-9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
26666Flag-mPar6a ΔPro136
26668Flag-mpar6a M235W
86148FLAG-mPar6a WTFLAG tagged mouse Par6 wild type - Binds to aPKC, Par3, Lgl, Cdc42
86149FLAG-mPar6a K19AFLAG-mPar6a K19A - Does not bind to aPKC

Antibodies from Article