L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system.
Miller DW, Ahmad R, Hague S, Baptista MJ, Canet-Aviles R, McLendon C, Carter DM, Zhu PP, Stadler J, Chandran J, Klinefelter GR, Blackstone C, Cookson MR
J Biol Chem. 2003 Sep 19. 278(38):36588-95.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
29340 | pcDNA3.1/GS-DJ1-R98Q-V5 | |
29341 | pcDNA3.1/GS-DJ1-E18N-V5 | |
29342 | pcDNA3.1/GS-DJ1-E18Q-V5 | |
29343 | pcDNA3.1/GS-DJ1-L166P-V5 | |
29344 | pcDNA3.1/GS-DJ1-E64D-V5 | |
29345 | pcDNA3.1/GS-DJ1-D149A-V5 | |
29346 | pcDNA3.1/GS-DJ1-E18D-V5 | |
29347 | pGW1-Myc-DJ1-WT | |
29349 | pGW1-Myc-DJ1-L166P/K130R |