Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.
Greggio E, Jain S, Kingsbury A, Bandopadhyay R, Lewis P, Kaganovich A, van der Brug MP, Beilina A, Blackinton J, Thomas KJ, Ahmad R, Miller DW, Kesavapany S, Singleton A, Lees A, Harvey RJ, Harvey K, Cookson MR
Neurobiol Dis. 2006 Aug . 23(2):329-41.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 25044 | pDEST53-LRRK2-WT | |
| 25045 | pDEST53-LRRK2-G2019S | |
| 25046 | pDEST53-LRRK2-R1441C | |
| 25048 | pDEST53-LRRK2-Y1699C | |
| 25049 | pDEST53-LRRK2-3XKD | |
| 25050 | pDEST53-LRRK2-3XKD-R1441C | |
| 25051 | pDEST53-LRRK2-3XKD-Y1699C | |
| 25052 | pDEST53-LRRK2-K1347A | |
| 25053 | pDEST53-LRRK2-ROC |