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The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

Lazzaretti D, Tournier I, Izaurralde E
RNA. 2009 Jun . 15(6):1059-66. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
25034pT7-EGFP-C1-HsTNRC6Biso1
25035pT7-EGFP-C1-HsTNRC6A
146083pCIneo-lambdaN-HA-HsAGO1_CMammalian Expression of HsAGO1
146084pCIneo-lambdaN-HA-HsAGO3_CMammalian Expression of HsAGO3
146085pCIneo-lambdaN-HA-HsAGO4_CMammalian Expression of HsAGO4
146086pCIneo-lambdaN-HA-HsTNRC6A_CMammalian Expression of HsTNRC6A
146087pCIneo-lambdaN-HA-HsTNRC6Biso1_CMammalian Expression of HsTNRC6Ciso1
146088pCIneo-lambdaN-HA-HsTNRC6Biso3_CMammalian Expression of HsTNRC6Biso3
146089pCIneo-lambdaN-HA-HsTNRC6C_CMammalian Expression of HsTNRC6C
146090pCIneo-RLuc_CMammalian Expression of Rluc
146091pCIneo-RLuc-5BoxB_CMammalian Expression of 5BoxB
146092pEGFP-N3-FLuc_CMammalian Expression of Fluc
146294pCIneo-lambdaN-HA-HsTNRC6A-C-term_FMammalian Expression of HsTNRC6A-Cterm
146295pCIneo-lambdaN-HA-HsTNRC6A-delAGOhook_FMammalian Expression of HsTNRC6A-delAGOhook
146296pCIneo-lambdaN-HA-HsTNRC6A-delMI_FMammalian Expression of HsTNRC6A-delMI
146297pCIneo-lambdaN-HA-HsTNRC6A-delMII_FMammalian Expression of HsTNRC6A-delMII
146298pCIneo-lambdaN-HA-HsTNRC6A-delMI-MII_FMammalian Expression of HsTNRC6A-delMI-MII
146299pCIneo-lambdaN-HA-HsTNRC6A-delMI-MII-AGOhook_FMammalian Expression of HsTNRC6A-delMI-MII-AGOhook
146300pCIneo-lambdaN-HA-HsTNRC6A-N-term_FMammalian Expression of HsTNRC6A-Nterm
146301pCIneo-lambdaN-HA-HsTNRC6Biso1-C-term_FMammalian Expression of HsTNRC6Biso1-Cterm
146302pCIneo-lambdaN-HA-HsTNRC6Biso1-delMI_FMammalian Expression of HsTNRC6Biso1-delMI
146303pCIneo-lambdaN-HA-HsTNRC6Biso1-delMII_FMammalian Expression of HsTNRC6Biso1-delMII
146304pCIneo-lambdaN-HA-HsTNRC6Biso1-delMI-MII_FMammalian Expression of HsTNRC6Biso1-delMI-MII
146305pCIneo-lambdaN-HA-HsTNRC6Biso1-N-term_FMammalian Expression of HsTNRC6Biso1-Nterm
146306pCIneo-lambdaN-HA-HsTNRC6C-C-term_FMammalian Expression of HsTNRC6C-Cterm
146307pCIneo-lambdaN-HA-HsTNRC6C-delAGOhook_FMammalian Expression of HsTNRC6C-delAGOhook
146308pCIneo-lambdaN-HA-HsTNRC6C-delMI_FMammalian Expression of HsTNRC6C-delMI
146309pCIneo-lambdaN-HA-HsTNRC6C-delMI-AGOhook_FMammalian Expression of HsTNRC6C-delMI-AGOhook
146310pCIneo-lambdaN-HA-HsTNRC6C-delMII_FMammalian Expression of HsTNRC6C-delMII
146311pCIneo-lambdaN-HA-HsTNRC6C-delMI-MII_FMammalian Expression of HsTNRC6C-delMI-MII
146312pCIneo-lambdaN-HA-HsTNRC6C-delMI-MII-AGOhook_FMammalian Expression of HsTNRC6C-delMI-MII-AGOhook
146313pCIneo-lambdaN-HA-HsTNRC6C-N-term_FMammalian Expression of HsTNRC6C-Nterm
146314pT7-EGFP-C1-HsAGO1_FMammalian Expression of HsAGO1
146315pT7-EGFP-C1-HsAGO2_FMammalian Expression of HsAGO2
146316pT7-EGFP-C1-HsAGO3_FMammalian Expression of HsAGO3
146317pT7-EGFP-C1-HsAGO4_FMammalian Expression of HsAGO4
146318pT7-EGFP-C1-MBP_FMammalian Expression of MBP

Antibodies from Article