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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer.

Bracken AP, Pasini D, Capra M, Prosperini E, Colli E, Helin K
EMBO J. 2003 Oct 15. 22(20):5323-35. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
24230pCMVHA hEZH2Mammalian expression of human EZH2 with HA tag
24231pCMVHA EED wtMammalian expression of human EED with HA tag

Antibodies from Article