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VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.

Tresse E, Salomons FA, Vesa J, Bott LC, Kimonis V, Yao TP, Dantuma NP, Taylor JP
Autophagy. 2010 Feb 22. 6(2):. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
23971VCP(wt)-EGFP
23972VCP(R155H)-EGFP
23973VCP(A232E)-EGFP
23974VCP(DK0)-EGFP

Antibodies from Article